The bragging rights remain at The Mac this season following an emphatic and entertaining 5-1 win away from home over Western Suburbs rivals Western Knights at Nash Field.
A brace from Alex Kretowicz and a goal each to Bryce Conway, Conor Devlin and Luke Randazzo sealed back-to-back derby wins this season.
Uni didn't have it all their way, with Knights well and truly on the front foot in the opening stages and deservedly took the lead after 15 minutes. A free-kick from the touch-line on the right wing flew in over Alex Preece's head with the 'keeper misjudging the flight of the ball.
The visitors hit back sharply, with Conway latching onto a half-cleared header on the right-hand corner of the box to volley home into the top corner.
Mordecai Junior showed his signature fast feet to open up space down the left-wing and whip in a dangerous cross into the area, which the Knights defence failed to clear and Conway levelled the scores.
The free-flowing and expansive nature of the contest continued until half time, but it remained 1-1 at the break.
UWA picked up where they left off in the second stanza, with the pace down both wings causing plenty of issues for the hosts.
Uni found themselves in the ascendancy in the 55th minute, with Devlin stepping up to convert a perfectly struck free-kick from 25-yards. Knights 'keeper Sam Stone's outstretched palm wasn't enough as the right-footed strike nestled into the bottom corner.
From that point on, it was all UWA. Midfield trio Devlin, Andrew Xydas and Randazzo began dictating the tempo, while the return of Tim Robertson in the heart of the back four proved vital as Knights struggled to create in the final third.
Kretowicz then continued his fine goal scoring fashion as he made it 3-1 and 4-1 in quick succession.
The striker, who is now a solitary strike away from being equal top of the Golden Boot standings, netted his first of the day from close-range after turning on a dime on the penalty spot following Tristan Taylor's cross.
It was an individual piece of brilliance for the second, with Robertson's well-weighted lofted through ball finding the striker, who then fought off the challenge from Graham Tough to calmly slot home from 10-yards.
Things went from bad to worse for Knights, with full-back David Michael receiving a straight red following an off the ball altercation with Devlin after 70 minutes.
Randazzo then sealed the memorable win with his first of the season. The midfielder received the ball on the edge of the area, shaped up to shoot, then cut inside onto his preferred right and dispatched into the bottom left corner to make it 5-1.
In other results, the 18's took another huge step towards the league title with a 5-2 win. The side are now five points clear at the top with two games still to play. The reserves suffered a narrow 1-0 defeat.